Arimidex (Anastrozole Tablets) used
Arimidex tablets 1mg are used to treat breast cancer in postmenopausal women, as first line therapy for early, advanced or metastatic breast cancer. Arimidex tablets 1mg are also used as additional treatment for early breast cancer in conjunction with other breast cancer treatment (tamoxifen) or if tamoxifen therapy has not helped prevent progression of the tumour.
Arimidex (Anastrozole Tablets) work
Arimidex tablets 1mg contain anastrozole, which is a potent and highly selective inhibitor of aromatase, an enzyme that is involved in the biosynthesis of the female hormone oestrogen. In premenopausal women the primary source of oestrogen production are the ovaries and oestrogen is involved in producing secondary sexual characteristics, such as breast development and in regulating the menstrual cycle. In postmenopausal women, when oestrogen production by the ovaries ceases, low levels of oestrogen are made in peripheral tissues, such as fat cells throughout the body, also some breast cancer cells, by conversion of androstenedione (produced by the adrenal glands) to estrone, due to the action of aromatase and then by further conversion to oestradiol (the most active form of circulating oestrogen. Many breast cancers have oestrogen receptors and their growth is stimulated by oestrogen; low levels of oestrogen may be sufficient to maintain growth of breast cancer cells in women with breast cancer. Anastrozole in Arimidex tablets 1mg blocks the action of aromatase, preventing the formation of oestrogen and helping to prevent growth of oestrogen-dependent breast tumours.
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